Liver disease can be inherited (genetic) and can also be a result of several underlying causes. The underlying causes include viral hepatitis, alcohol-related liver disease or non-alcoholic fatty liver disease, chronic alcohol abuse, certain prescription or over-the-counter medications, certain herbal compounds, genetics, immune system abnormalities and cancer.
Liver disease, when left untreated, can lead to several complications. These include varices, ascites, hepatic encephalopathy (HE), hepatopulmonary hypertension, hepatocellular carcinoma, hepatorenal syndrome, spontaneous bacterial peritonitis, and coagulation disorders.
To prevent these complications, laboratory diagnosis must be done whenever the symptoms of liver disease are observed.
Laboratory diagnosis for the liver disease includes Liver Function Tests and Liver Biopsy.
Liver function tests are blood tests that help to diagnose and to monitor liver disease and the extent of damage to the liver. A liver biopsy is often recommended in the case of irregular blood test results in the presence of a tumour or other irregularities in the liver.
Laboratory diagnosis of liver disease provides information that helps to provide the appropriate treatment plan for individuals. It also helps to monitor the progression of the disease, possible side effects of medications and the response of patients to treatment. In the case of a liver transplant, laboratory diagnosis also helps to monitor the liver after a liver transplant.
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References:
www.mayoclinic.org
www.ncbi.nlm.nih.gov